ISHLTv_10 - Update on COVID-19 and Challenges in Cardiothoracic Transplantation

Description

Scientific Program

Session Summary:
The ongoing COVID-19 pandemic has had significant global impact on cardiothoracic transplantation. The ISHLT COVID-19 webinar will discuss various aspects of the pandemic on heart and lung transplantation using a case-based approach. Topics include infectivity of SAR-CoV-2, management of wait listed patients infected with or exposed to SARS-CoV-2, summary of recent COVID-19 therapeutic trials and implications for transplant recipients, and lung transplant evaluation and listing criteria for COVID-19 related respiratory failure. Faculty will be available for a live Q&A session.

Moderators: Fernanda Silveira, MD, and Stephan Ensminger, MD, DPhil

Welcome and Program Panel Introduction
Fernanda Silveira, MD, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

Case Presentation: Patient on the Waitlist with Persistent Positive PCR
Jonathan Hand, MD, Ochsner Medical Center, New Orleans, LA, USA

Infectivity of SARS-CoV-2
Shahid Husain, MD, MS, University Health Network, Toronto, ON, Canada

This talk will discuss the infectiousness and detection of SARS-CoV-2 with respect to incubation period as well as time and severity of illness with a focus on data regarding viral cultures and PCR results.

Waitlist Management of Patients Infected With or Exposed To SARS-CoV-2
Enrico Ammirati, MD, PhD, Asst Grande Ospedale Metropolitano Niguarda, Milan, Italy

The infectiousness of SARS-CoV-2 is of particular clinical relevance in waitlisted candidates with COVID-19 who resolve symptoms of infection but continue to have positive PCRs and the timing of waitlist activation. Additionally, the speaker will discuss inactivation of patients on the waitlist with known exposure to a confirmed case of COVID-19.

Case Presentation: Transplant Recipient With COVID-19
Paola Morejon Barragan, MD, Instituto Argentino de Diagnostico y Tratamiento, Buenos Aires, Argentina

COVID-19 Targeted Therapies
Robin Avery, MD, Johns Hopkins Hospital, Baltimore, MD, USA

This presentation will focus on clinical trials for management of COVID-19 and take home messages from these trials that are pertinent to transplant recipients, as well as recommendations for immunosuppression management (especially if a patient receives dexamethasone).

Case Presentation: Non-Transplant Patient with COVID-19 Related Respiratory Failure
Caroline Patterson, BMBS BMedSci MD, Royal Papworth Hospital, Cambridge, United Kingdom

Lung Transplant for COVID-19
Konrad Hoetzenecker, MD, Medical University of Vienna, Vienna, Austria

This talk will discuss evaluation and listing criteria for patients with COVID-19 related ARDS as well as surgical challenges and post-transplant immunosuppression

Q & A Segment with All Faculty
Led by Stephan Ensminger, MD, DPhil, University of Lubeck, Lubeck, Germany

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ISHLT COVID-19 Task Force Update
Saima Aslam, MD, MS, UCSD, San Diego, CA, USA
COVID-19 Task Force Chair

ISHLT Announcements
Greg Schultz, CEO, ISHLT, Addison, TX, USA

Speaker(s):

• Fernanda Silveira, MD, MS, FIDSA, Pittsburgh, PA, USA, University of Pittsburgh Medical Center
• Stephan Ensminger, MD, DPhil, Lubeck, Germany, University Heart Center Lubeck
• Jonathan Hand, MD, New Orleans, LA, USA, Ochsner Medical Center
• Shahid Husain, MD, MS, University Health Network, Toronto, ON, Canada
• Enrico Ammirati, MD, PhD, Milano, Italy, Niguarda Hospital
• Paola Morejon Barragan, Buenos Aires, Argentina, Instituto Argentino de Diagnostico y Tratamiento
• Robin Avery, MD, FIDSA, FAST, Baltimore, MD, USA, Johns Hopkins
• Caroline Patterson, MD, Cambridge, United Kingdom, Royal Papworth Hospital
• Konrad Hoetzenecker, MD, PhD, Vienna, Austria, Medical University of Vienna
• Saima Aslam, MD, MS, Associate Professor; Director, Solid Organ Transplant Infectious Diseases; Division of Infectious Diseases and Global Public Health, University of California, San Diego, CA, USA
• Greg Schultz, CEO, Addison, TX, USA, International Society for Heart and Lung Transplantation