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ISHLTv_05 - Pulmonary Hypertension: Where We're Going We Don't Need Roads

Jul 22, 2020 9:00am ‐ Jul 22, 2020 10:30am

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An ISHLT 2020 Oral Session Presentation

Scientific Program Agenda:

Moderator:
Sarah Medrek, MD, University of New Mexico, Albuquerque, NM, USA

Welcome, Session Overview
Oksana Shlobin, MD, Inova Fairfax Hospital, Falls Church, VA, USA
Liaison, ISHLT 2020 Program Committee PH Group

Program Introduction
Moderator

(12) Results from the REPAIR Study: Effects of Macitentan on Right Ventricular (RV) Remodelling in Pulmonary Arterial Hypertension (PAH)

A. Vonk Noordegraaf¹, R. Channick², E. Cottreel³, D. Kiely⁴, N. Martin³, O. Moiseeva⁵, A. Peacock⁶, A. Tawakol⁷, A. Torbicki⁸, S. Rosenkranz*⁹, N. Galiè* (*co-last authors)¹⁰. ¹Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands, ²David Geffen School of Medicine at UCLA, Los Angeles, CA, ³Actelion Pharmaceuticals Ltd, Allschwil, Switzerland, ⁴Royal Hallamshire Hospital, Sheffield, United Kingdom, ⁵Almazov National Medical Research Centre, St Petersburg, Russian Federation, ⁶Scottish Pulmonary Vascular Unit, Glasgow, United Kingdom, ⁷Massachusetts General Hospital and Harvard Medical School, Boston, MA, ⁸Department of Pulmonary Circulation CMKP at European Health Center, Otwock, Poland, ⁹Heart Center at the University of Cologne, and Cologne Cardiovascular Research Center (CCRC), Cologne, Germany, ¹⁰Department of Experimental, Diagnostic and Specialty Medicine – DIMES, University of Bologna, Bologna, Italy

(14) INSPIRE: Final Results from a Phase 3, Open-Label, Pivotal Study to Evaluate the Safety and Tolerability of LIQ861 in Pulmonary Arterial Hypertension

N. S. Hill¹, J. P. Feldman², S. Sahay³, D. Levine⁴, R. F. Roscigno⁵, T. A. Vaughn⁵, T. M. Bull⁶. ¹Pulmonary, Tufts Medical Center, Boston, MA, ²Arizona Pulmonary Specialists, Phoenix, AZ, ³Houston Methodist Hospital, Houston, TX, ⁴University of Texas Health Sciences Center at San Antonio, San Antonio, TX, ⁵Liquidia Technologies, Morrisville, NC, ⁶Anschutz Medical Campus, University of Colorado Denver, Aurora, CO

(15) The Relationship between Pulmonary Artery Pulse Pressure and Pulmonary Artery Wedge Pressure during Exercise in Health and in Patients with Suspected Pulmonary Hypertension

R. F. Bentley¹, M. Barker¹, S. Esfandiari¹, S. P. Wright¹, F. H. Valle¹, J. T. Granton², S. Mak¹. ¹Division of Cardiology, Sinai Health System, Toronto, ON, Canada, ²Division of Respirology, University Health Network, Toronto, ON, Canada

(16) Validation of REVEAL Risk Score Calculator 2.0 in Patients with PAH in the Phase III PATENT Study

R. L. Benza¹, H. W. Farber², A. E. Frost³, H. A. Ghofrani⁴, P. A. Corris⁵, B. Brockmann⁶, S. Nikkho⁷, C. Meier⁸, M. M. Hoeper⁹. ¹Ohio State University, Columbus, OH, ²Pulmonary Hypertension Center, Boston University/Boston Medical Center, Boston, MA, ³Department of Medicine, Houston Methodist, Houston, TX, ⁴Member of the German Center for Lung Research (DZL), University of Giessen and Marburg Lung Center (UGMLC), Glessen, Germany, ⁵Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, ⁶CHRESTOS Concept GmbH & Co. KG, Essen, Germany, ⁷Global Clinical Development, Bayer AG, Berlin, Germany, ⁸Global Medical Affairs, Bayer AG, Berlin, Germany, ⁹Clinic for Respiratory Medicine, Hannover Medical School, member of the German Center for Lung Research (DZL), Hannover, Germany

(17) Patients with Methamphetamine-Associated Pulmonary Arterial Hypertension Have Less Favorable Hemodynamics Than Other Patients with Group 1 PAH

E. Vasti¹, A. Papolos², N. A. Kolaitis³, J. Mayfield³, G. H. Tison², T. De Marco⁴. ¹Department of Medicine, University of California, San Francisco, San Francisco, CA, ²Department of Medicine, Division of Cardiology, University of California, San Francisco, San Francisco, CA, ³Department of Medicine, Division of Pulmonology, University of California, San Francisco, San Francisco, CA, ⁴Department of Medicine, Division of Cardiology, University of California, San Francisco, University of California, CA

(18) Right Atrial Pacing to Improve Acute Hemodynamics in Pulmonary Arterial Hypertension

J. S. Khural¹, B. A. Houston¹, P. J. Leary², S. C. Mathai³, T. M. Kolb³, R. Damico³, H. M. Paul³, D. A. Kass⁴, S. Hsu⁴, R. J. Tedford¹. ¹Division of Cardiology, Department of Medicine, The Medical University of South Carolina, Charleston, SC, ²Division of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Washington, Seattle, WA, ³Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, ⁴Division of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD

Q & A Segment with all presenters
Led by Moderator

ISHLT Pulmonary Vascular Disease Interdisciplinary Network Update
Ioana Preston, MD, Tufts Medical Center, Boston, MA, USA
Chair, Pulmonary Vascular Disease Interdisciplinary Network Steering Committee

ISHLT Announcements
Greg Schultz, CEO, ISHLT, Addison, TX, USA

Adjourn

Speaker(s):

Sarah Medrek, MD, Assistant Professor, University of New Mexico, Albuquerque, NM, USA
Oksana Shlobin, MD, Medical Director, Pulmonary Hypertension Program; Director of Education, Advanced Lung Disease and Transplant Program, Inova Fairfax Hospital, Falls Church, VA, USA
Anton Vonk Noordegraaf, MD, Chair of the Dept of Pulmonary Medicine, Amsterdam University Medical Center, Amsterdam, Netherlands
Nicholas Hill, MD, Chief, Div of Pulmonary, Critical Care and Sleep Medicine, Tufts Medical Center, Boston, MA, USA
Robert Bentley, PhD, Faculty of Kinesiology & Physical Education, Division of Cardiology, Sinai Health System, University of Toronto, Toronto, Ontario, Canada
Raymond L. Benza, MD, FACC, FAHA, FACP, Professor and Director, Division of Cardiovascular Diseases; Bob and Corrine Frick Endowed Chair of Heart Failure, Department of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA
Elena Vasti, MD, MPH, Internal Medicine Resident, Stanford University School of Medicine, Stanford, CA, USA
Jasjeet Khural, MD, Cardiology Fellow, Medical University of South Carolina, Charleston, SC, USA
Ioana R. Preston, MD, Boston, MA, USA, Tufts Medical Center
Greg Schultz, CEO, Addison, TX, USA, International Society for Heart and Lung Transplantation

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