2017 Annual Meeting

Apr 5, 2017 ‐ Apr 8, 2017

SYMPOSIUM 1: Joint ISHLT/ICCAC Symposium: Besides the Surgery - How to Make VAD Patients Successful

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SYMPOSIUM 1: Joint ISHLT/ICCAC Symposium: Besides the Surgery - How to Make VAD Patients Successful

Apr 5, 2017 8:00am ‐ Apr 5, 2017 10:00am

Identification: SYM01

Multidisciplinary Approaches to Optimize VAD Patient Management in High Volume Centers
Friedrich Kaufmann, MSc

Caring for the Pediatric VAD Patient - They Aren't Just Small Adults
Jodie Lantz, MSN, RN, PCNS-BC

Keep Them at Home: Interventions to Prevent Readmission
Lori Edwards, MSN

Measuring and Managing Blood Pressure in CF-LVAD recipients
Brent Lampert, DO

Echocardiography in LVAD Recipients: How and What to Measure?
Peter Bergin, MBBS, FRACP

Optimizing Unloading with Right Heart Catheterization Ramp Studies
Nir Uriel, MD

Do We Need Antiplatelet Drugs and Anticoagulants to Manage LVAD Patients?
Haifa Lyster, MSc

• Friedrich Kaufmann, Dipl.Eng., German Heart Center Berlin
• Jodie Lantz, MSN, RN, PCNS-BC, Children's Health Dallas, Richardson, TX, USA
• Lori Edwards, MSN, Inova Fairfax Hospital
• Brent Lampert, DO, Ohio State University
• Peter Bergin, MBBS, FRACP, Alfred Hospital, Melbourne, Australia
• Nir Uriel, MD, MSc, University of Chicago, Chicago, IL, United States
• Haifa Lyster, MSc, Specialist Transplant Pharmacist, Royal Brompton & Harefield NHS Foundation TrustRoyal Brompton, Middlesex, United Kingdom

SYMPOSIUM 2: When Should We Call It Quits? The Efficacy of Interventions to Ameliorate Psychosocial Risk Factors

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SYMPOSIUM 2: When Should We Call It Quits? The Efficacy of Interventions to Ameliorate Psychosocial Risk Factors

Apr 5, 2017 8:00am ‐ Apr 5, 2017 10:00am

Identification: SYM02

The Impact of Psychiatric Risk Factors on Outcomes in Heart Failure, MCS and Cardiothoracic Transplant Patients
Heike Spaderna, PhD

The Efficacy of Interventions for Psychiatric Risk Factors in Cardiothoracic Transplantation and MCS
Quincy Young, PhD, RPsych

It Takes a Village: Social Support and Social Determinants of Health in MCS and Cardiothoracic Transplantation as Potential Targets for Intervention
Michael Petty, PhD, RN, CNS

When Do We Call It Quits: Intervention Strategies and Outcomes for Medical Non-Adherence
Mary Dew, PhD

Are All Substances Made Equal?
Andrea DiMartini, MD

Case Presentation (Part 1): The Good, The Bad And The Ugly
Jay Baumwol, MBBS, FRACP

Case Presentation (Part 2): The Good, The Bad And The Ugly
Gillian Coult, BSW

• Heike Spaderna, PhD, University of Trier
• Quincy Young, PhD, RPsych, St. Paul's Hospital Vancouver, BC, CANADA
• Michael G. Petty, PhD, RN, CNS, University of Minnesota,Minneapolis, MN, USA
• Mary Amanda Dew, PhD, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States
• Andrea DiMartini, MD, University of Pittsburgh
• Jay Baumwol, MBBS, FRACP, Fiona Stanley Hospital
• Gillian Coult, BSW, Alfred Hospital

SYMPOSIUM 3: Primary Graft Dysfunction (PGD) and Vasoplegia After Heart Transplantation: Sink or Swim

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SYMPOSIUM 3: Primary Graft Dysfunction (PGD) and Vasoplegia After Heart Transplantation: Sink or Swim

Apr 5, 2017 8:00am ‐ Apr 5, 2017 10:00am

Identification: SYM03

Review of the Published Literature and the ISHLT 2014 PGD Definition
Jon Kobashigawa, MD

Review of Risk Factors for PGD: Donor, Recipient, and Surgical Procedure
Jennifer Cook, MD

First Prospective Observational Study on PGD: UK The Heart Evaluation and Retrieval for Transplantation Study
Andre Simon, MD, PhD

Vasoplegia after Adult Heart Transplantation and MCS Surgery
Maria Patarroyo Aponte

Severe PGD and Post-Operative Vasoplegia: Complications on the Same Spectrum or Different Entities?
Hiroo Takayama, MD

What Can We Learn from Non-Transplant Cardiac Surgery?
Paul Mohacsi, MD

• Jon Kobashigawa, MD, Cedars-Sinai Smidt Heart Institute, Los Angeles, CA, United States
• Jennifer Cook, MD, University of Arizona Heart Center
• Andre Simon, MD, PhD, Harefield Hospital
• Maria Patarroyo Aponte, MD, Allegheny General Hospital
• Hiroo Takayama, MD, PhD, Columbia University
• Paul Mohacsi, MD, University Hospital

SYMPOSIUM 4: Thinking Outside the Box: Extra-Pulmonary Management in Lung Transplantation

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SYMPOSIUM 4: Thinking Outside the Box: Extra-Pulmonary Management in Lung Transplantation

Apr 5, 2017 8:00am ‐ Apr 5, 2017 10:00am

Identification: SYM04

Gastro-Intestinal Dysmotility in Thoracic Organ Transplantation Revisited: Importance, Evaluation, Treatment
Frank D'Ovidio

Gastro-Intestinal Malignancies in Thoracic Organ Transplantation: Collateral Damage?
Monique Malouf, MD

New Lungs - Old Sinuses: Friends or Foes?
Joseph Pilewski, MD

Lung Transplantation in Systemic Disorders: Need for a Holistic Approach
Joseph Lynch, MD

Pregnancy After Thoracic Organ Transplantation: Unwanted But Unavoidable?
Mitesh Thakrar, MD

• Frank D'Ovidio, MD, Columbia University
• Monique Malouf, FRACP, St. Vincent's Hospital
• Joseph Pilewski, MD, University of Pittsburgh Medical Center
• Joseph Lynch, MD, UCLA Medical Center
• Mitesh Thakrar, MD, University of Calgary

SYMPOSIUM 5: Joint ISHLT/PHA Symposium: PH and Transplant: Where Do We Go From Here?

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SYMPOSIUM 5: Joint ISHLT/PHA Symposium: PH and Transplant: Where Do We Go From Here?

Apr 5, 2017 8:00am ‐ Apr 5, 2017 10:00am

Identification: SYM05

Transplantation for PH in the Era of LAS
Roham Zamanian, MD

Effect of Non-Group 1 Pulmonary Hypertension on Lung Transplantation
Jorn Carlsen, MD, DMSc

Saving the Lung: Liver Transplant in Portopulmonary Hypertension
Sonja Bartolome, MD

Oops: Pregnancy in Pulmonary Hypertension
Valerie McLaughlin, MD

Challenging Choices: Switching between IV and Oral Prostanoid Therapy
Joel Wirth, MD

Quality of Life is Most Important: Patient Related Outcomes in PH
Mardi Gomberg-Maitland, MD

• Roham Zamanian, MD, Stanford University
• Jorn Carlsen, MD, DMSc, Copenhagen University Hospital
• Sonja Bartolome, MD, University of Texas, Southwestern Medical Center, Dallas, TX, United States
• Valerie McLaughlin, MD, University of Michigan
• Joel Wirth, MD, Maine Medical Center
• Mardi Gomberg-Maitland, MD, Inova Fairfax Hospital, Falls Church, VA, United States

SYMPOSIUM 6: The Failing Fontan - Where Do We Go From Here?

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SYMPOSIUM 6: The Failing Fontan - Where Do We Go From Here?

Apr 5, 2017 8:00am ‐ Apr 5, 2017 10:00am

Identification: SYM06

Sustainable Palliation: Optimizing Fontan Patients Prior to Heart Transplant
Jack Rychik, MD

Call for Help! Surgical Options for End-Stage Fontan Failure
Asif Hasan, MD

Do You Want to List Too Early or Too Late? How to Determine When Fontan Patients Should be Listed for Transplant
Claire Irving, MBChB, MRCPCH, MD

It's Not JUST the Heart: Multi-Organ Transplantation in Fontan Patients
Daniel Bernstein, MD

Will Anybody Still Transplant My Patient? Programmatic Issues With Taking On Complex Fontan Patients
Richard Kirk, FRCP, FRCPCH

Case Presentation - The Failing Fontan Patient
Kathleen Simpson, MD

• Jack Rychik, MD, Children's Hospital of Philadelphia
• Asif Hasan, MD, Freeman Hospital
• Claire Irving, MBChB, MRCPCH, MD, Children's Hospital Westmead, Sydney, Australia
• Daniel Bernstein, MD, Stanford University
• Richard Kirk, FRCP, FRCPCH, UT Southwestern Medical Center
• Kathleen Simpson, MD, Washington University/St. Louis Children's Hospital, St. Louis, MO, United States

SYMPOSIUM 7: Joint ISHLT/ESCMID Symposium: Ongoing Challenges in Transplant Infectious Diseases

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SYMPOSIUM 7: Joint ISHLT/ESCMID Symposium: Ongoing Challenges in Transplant Infectious Diseases

Apr 5, 2017 8:00am ‐ Apr 5, 2017 10:00am

Identification: SYM07

Non-Cultural Methods for Diagnosis and Prevention of Invasive Fungal Infections: Are We There Yet?
Barbara Alexander, MD

Role of Inhaled Antimicrobials in the Era of Multidrug Resistance
Benoit Guery, MD

Infection in Thoracic Organ Transplant Recipients on ECMO
Nicolas Mueller, MD

Hepatitis C in Donor and Thoracic Organ Transplant Candidates and Recipients: A New Horizon
Paolo Grossi, MD, PhD

Experience in HIV Infection in Thoracic Organ Transplantation and MCS
Shirish Huprikar, MD

EBV and Anellovirus Viremia as Markers of Risk of Infection in Lung Transplant Recipients
José Maria Aguado, MD

• Barbara Alexander, MD, Duke University
• Benoit Guery, MD, University Hospital Vaudois
• Nicolas Mueller, MD, University Hospital Zurich, Zurich, Switzerland
• Paolo A. Grossi, MD, PhD, Professor of Infectious Diseases, University of Insubria, Varese, Italy
• Shirish Huprikar, MD, Mount Sinai Medical Center
• José Maria Aguado, MD, Hospital 12 de Octubre

OPENING PLENARY SESSION

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OPENING PLENARY SESSION

Apr 5, 2017 10:30am ‐ Apr 5, 2017 12:30pm

Identification: PL1

Welcome/Program Chair Report
Jeffrey Teuteberg, MD

Thoracic Registry Report
Josef Stehlik, MD, MPH

MCSD Registry Reports
James L Kirklin, MD

President's Report
Maryl R Johnson, MD

(1) The Treatment of Patients with Advanced Heart Failure Ineligible for Cardiac Transplantation with the HeartWare Ventricular Assist Device: Results of the ENDURANCE Supplement Trial
Carmelo Milano, MD

Interactive Discussant
Vivek Rao, MD

(2) The Impact of Age, Sex, Therapeutic Intent and Severity of Advanced Heart Failure on Outcomes in the Multicenter Study of Maglev Technology in Patients Undergoing Mechanical Circulatory Support Therapy with Heartmate 3 (Momentum 3) Pivotal Trial
Daniel Goldstein, MD

Interactive Discussant
Jan Schmitto

Pioneer Award Recipient Lecture: Standing on the Shoulders of Giants
Stuart W Jamieson, MB, FRCS

• Jeffrey J. Teuteberg, MD, Stanford University School of Medicine, Stanford, CA, United States
• Josef Stehlik, MD, MPH, University of Utah School of Medicine, Salt Lake City, UT, United States
• James K. Kirklin, MD, University of Alabama
• Maryl Johnson, MD, ISHLT President
• Carmelo Milano, MD, Duke University Medical Center, Durham, NC, United States
• Vivek Rao, MD, PhD, Toronto General Hospital
• Daniel Goldstein, MD,FACS,FACC, Montefiore Medical Center, Bronx, NY, United States
• Jan Schmitto, MD, PhD, Hannover Medical School
• Stuart Jamieson, MB, FRCS, ISHLT Past President, 1986-1988

SESSION 1: Too Thick or Too Thin? Bleeding and Thrombosis in MCS

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SESSION 1: Too Thick or Too Thin? Bleeding and Thrombosis in MCS

Apr 5, 2017 2:30pm ‐ Apr 5, 2017 4:00pm

Identification: 001

(3) Plasma Free Hemoglobin Activates Platelets and Protects Von Willebrand Factor from Degradation: Clinical and In Vitro Evidence That LVAD Hemolysis Causes LVAD Thrombosis
Carlo Bartoli, MD, PhD

(4) The Effect of Pre-Existing Hypercoagulable Disorders on Outcomes in Patients with LVADs
Sirtaz Adatya, MD

(5) Standard Dose Doxycycline Does Not Alter von Willebrand Factor Degradation in Patients with CF LVAD
Mary Keebler, MD

(6) Platelet Membrane-Related Morphologic Alterations: An Early Marker of Supra-Physiologic Shear-Mediated Platelet Activation Associated with VADs
Marvin J. Slepian, MD

(7) Novel Analysis of High-Molecular-Weight Von Willebrand Factor Multimers Predicts Bleeding Events
Samson Hennessy-Strahs, BA

(8) Managing Anticoagulation in LVAD Patients: The Harefield Experience
Rachel Hards, RGN

• Carlo Bartoli, MD, PhD, University of Pennsylvania
• Sirtaz Adatya, MD, University of Chicago Medical Center
• Mary Keebler, MD, Vanderbilt University Medical Center
• Marvin Slepian, MD, University of Arizona
• Samson Hennessy-Strahs, BA, University of Pennsylvania
• Rachel Hards, RGN, Harefield Hospital

SESSION 2: Engineering for Perfection in MCS

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SESSION 2: Engineering for Perfection in MCS

Apr 5, 2017 2:30pm ‐ Apr 5, 2017 4:00pm

Identification: 002

(9) Mechano-Acoustic Detection of Dysfunction in Continuous Flow VADs Utilizing Stretchable Electronic Systems
Marvin Slepian, MD

(10) Virtual Implantation of the Infant Jarvik 2015 for Eligibility Criteria Establishment
Justin Ryan, PhD

(11) A Novel, Implantable Device for Right-Side Mechanical Circulatory Support
James Stanfield, PhD

(12) Pulsatile Outflow in Cows Supported Long-Term with the BiVACOR Rotary TAH
William Cohn, MD

(13) Primary Biventricular Durable Ventricular Assist Devices from Experience North American Centers: A Cautionary Tale
Palak Shah, MD, MS

(14) Is ICD Implantation Necessary in Patients with Left Ventricular Assist Device Therapy?
Aitor Uribarri, MD

• Marvin Slepian, MD, University of Arizona
• Justin Ryan, PhD, Phoenix Children's Hospital
• James Stanfield, PhD, University of Utah
• William Cohn, MD, Texas Heart Institute
• Palak Shah, MD, MS, Inova Heart and Vascular Institute, Falls Church, VA, United States
• Aitor Uribarri, MD, Hannover Medical School